Journal of Economic Animal

Effects of Oligosaccharides, Yeast and Its Derivatives on Health and Production Performance of Equine Animals: A Research Progress

Research Progress on Nutritional Requirements and Utilization of Feed Resources in Breeding Rabbits

IGF1R Gene Copy Number Variation Associated with Growth Traits in Different Cattle Breeds

Preservation Effect Analysis of Langya Chicken Hens Based on Their Growth Curve

Identification of Candidate Genes for Body Weight in Sika Deer(Cervus nippon) Based on Genome-Wide Selection Signature Analysis

Body weight is an important economic trait for evaluating meat production performance in sika deer (Cervus nippon). To identify candidate genes associated with body weight， body weight phenotypic data of 100 healthy 5-year-old adult male sika deer under uniform feeding and management conditions at the Guangcai Sika Deer Farm of Beixing Farm， Hongxinglong Reclamation Area， Heilongjiang Province were used in this study. Individuals were ranked by body weight， and the top 20 and bottom 20 individuals were selected to form the high body weight group (HW) and low body weight group (LW)， respectively. Whole-genome resequencing combined with fixation index (Fst) analysis was performed to detect selection signatures associated with body weight differences between the two groups. A total of 18，460，510 high-quality single nucleotide polymorphisms (SNPs) were identified across the genome. Principal component analysis (PCA) showed clear molecular-level separation between the HW and LW groups. Using the top 5% of Fst values as the threshold， 851 candidate genes were screened. Gene Ontology (GO) enrichment analysis showed that these candidate genes were significantly enriched in functional categories related to ion channel activity， transmembrane transporter activity， and cytoskeletal organization. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed significant enrichment in pathways associated with muscle cytoskeleton， regulation of lipolysis in adipocytes， and protein digestion and absorption. Comprehensive analysis identified four key candidate genes: TTN， NEB， PDE3B， and IRS4， which are closely related to muscle development， lipid metabolism， and energy homeostasis. These genes may serve as important molecular markers for genetic improvement of body weight traits in sika deer and provide a theoretical basis for molecular breeding of meat-type sika deer.

Research Progress on the Design of Interactive Pet Toys Based on Cognitive and Behavioral Characteristics of Dogs and Cats

During the long process of coevolution with humans， dogs and cats have formed unique interspecific social cognitive abilities different from other animals. At present， research on social cognition， animacy perception and interactive pet toys for dogs and cats has made certain achievements， but there are still gaps. This paper reviews the research progress of behavioral welfare needs， hunting behavior mechanism， animacy perception， cognition of inanimate interactive agents and intelligent toys for dogs and cats， expounds the characteristics of social cognition and animacy dynamic perception of dogs and cats， and points out that follow-up research should improve the long-term welfare evaluation of toys on pets， strengthen the research on cat cognition， and develop more personalized intelligent toy products.

Effect of Lactobacillus Salivarius on Sperm Motility in High-fat Diet-fed Mice

Lactobacillus salivarius is a probiotic; however， its effect on sperm motility remains unclear. To investigate the effect of Lactobacillus salivarius on sperm motility， a mouse model of reduced sperm motility was established by high-fat diet feeding， and the effects of Lactobacillus salivarius on sperm motility and sperm count were analyzed. The results showed that， compared with the control group， sperm motility in the high-fat diet group was significantly decreased (P < 0.01). Compared with the high-fat diet group， sperm count in the Lactobacillus salivarius group was significantly increased (P < 0.05). In addition， compared with the control group， sperm count in the high-fat diet group was markedly decreased (P < 0.01). In conclusion， Lactobacillus salivarius markedly improved sperm quality in mice with low sperm motility induced by a high-fat diet and may serve as a potential probiotic.

Effects of Deer-Derived Enterotoxigenic Escherichia coli and Salmonella on Intestinal Gene Expression in Mice

Diarrhoea in fawns induced by Escherichia coli and Salmonella can cause damage to the intestinal mucosa， immune dysregulation and digestive dysfunction. To investigate changes in host intestinal transcriptional levels following separate infections with E. coli and Salmonella， the causative agents of fawn diarrhoea， and to identify differentially expressed genes associated with the immune response， this study established a mouse infection model. Intestinal tissues were collected from infected mice and analysed using RNA-Seq technology for transcriptomic sequencing. RNA-Seq results revealed that， compared with normal， uninfected mice， E. coli-infected mice exhibited 1，866 significantly differentially expressed genes (DEGs)， comprising 845 up-regulated genes and 1，021 down-regulated genes; Salmonella-infected mice exhibited 2，566 significantly differentially expressed genes (DEGs)， comprising 1，144 up-regulated genes and 1，422 down-regulated genes. GO functional enrichment analysis indicated that the differentially expressed immune-related genes were primarily associated with defence responses， responses to external stimuli， inflammatory responses， and immune-related processes. KEGG pathway enrichment analysis revealed that the differentially expressed genes were mainly involved in cytokine-cytokine receptor interactions， the TNF signalling pathway， the IL-17 signalling pathway， the NOD-like receptor signalling pathway， and the complement and coagulation cascade; These pathways collectively participate in the regulation of intestinal inflammation and immune responses， playing a crucial regulatory role in the onset and progression of bacterial diarrhoea. Finally， qRT-PCR was employed to validate the differentially expressed genes， and the results were largely consistent with the transcriptomic findings. This study provides a scientific basis for further investigation into the mechanisms underlying changes in host intestinal inflammation and immune responses caused by E. coli and Salmonella infections in fawns..

Analysis of the Molecular Characteristics of the CDS Region of the Sheep CatSper4 Gene and its Expression in the Testes at Different Stages

The sperm cation channel (CatSper) is a specific calcium ion channel located on the membrane of sperm cells. CatSper4 acts as the core sub-unit of this channel. Its main function is to regulate calcium ions flow and sperm hyperactivation. In this study， the molecular characteristics of CDS region of sheep CatSper4 gene were studied by bioscientific analysis and systematic evolution tree was constructed. The expression of the CatSper4 gene and protein in the testes of sheep at different stages of development (2，6 and 12 months of age) was measured using real-time fluorescence measurement (qRT-PCR) and protein immunosignature (Western-blot). The results showed that the CDS region of sheep CatSper4 gene was 1341 bp long， encoding 460 amino acids. The theoretical isoelectric point (pi) of the protein is 10.85， which is an unstable hydrophilic protein with transmembrane region， no signal peptide sequence and 61 phosphorylation sites.Both the secondary structure and the tertiary structure are composed of alpha-helix， irregular curvature and β-folding and may be related toCatSper1、CatSper2、CatSper3、CatSperB、CatSperD、CatSperG、CatSperE、TMEM262、TMEM249And EFCAB9 protein. The similarity of CDS region of sheep CatSper4 gene to goat， cattle and deer was higher than 96%. The similarity with a domestic donkey was lower at 85.23%.The expression of CatSper4 gene and protein in testis of sheep at three developmental stages increased with the growth of age， and the difference of expression was significant (P<0.01). Therefore， the expression of CatSper4 in different developmental stages of sheep testis is different， indicating that it plays an important role in the regulation of spermatogenesis. The results of this study provide important scientific basis and theoretical reference for further study on the function and mechanism of male reproduction in CatSper4 sheep.

A Study on the Extraction Separation and Anticancer Activity of Velvet Antler Protein

Application of Ecological Niche Models for Selection of Species Habitat

Advances on the Chemical Components and Pharmacological Activities of Velvet Antler

The Effect of the Alcohol Extract of Pilose Antler on the Red Blood Cells′ Immunologic Function in the Mice Treated by Cyclophosphamide

Pathogens of Intestinal Diseases in Giant Panda

Interpretation of Development of Chinese Pet industry in 2024

Utilization of Resources Insects

Advances on the Chemical Components and Pharmacological Activities of Velvet Antler

Research Progress of Immune Adjuvant

Advanceson Heat Shock Protein